Heavier alkaline earth catalyzed ene-yne cyclizations: atom-efficient access to tetrahydroisoquinoline frameworks.
نویسندگان
چکیده
Tetrahydroisoquinoline frameworks may be accessed with 100% atom efficiency through the alkaline earth catalyzed addition of primary amines to ene-yne substrates through a sequence of intermolecular alkene and intramolecular alkyne hydroamination steps.
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عنوان ژورنال:
- Organic letters
دوره 16 22 شماره
صفحات -
تاریخ انتشار 2014